Triethylamine → N-(3-(1-(2-(7-Methoxyquinolin-4-yloxy)ethyl)-6-oxo-1,6-dihydropyridin-3-yl)prop-2-ynyl)-2-(pyrrolidin-1-yl)acetamide

반응식

Br[C:2]1[CH:3]=[CH:4][C:5](=[O:23])[N:6]([CH2:8][CH2:9][O:10][C:11]2[C:20]3[C:15](=[CH:16][C:17]([O:21][CH3:22])=[CH:18][CH:19]=3)[N:14]=[CH:13][CH:12]=2)[CH:7]=1.C(N(CC)CC)C.[CH2:31]([NH:34][C:35](=[O:42])[CH2:36][N:37]1[CH2:41][CH2:40][CH2:39][CH2:38]1)[C:32]#[CH:33]>Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[Cu]I>[CH3:22][O:21][C:17]1[CH:16]=[C:15]2[C:20]([C:11]([O:10][CH2:9][CH2:8][N:6]3[C:5](=[O:23])[CH:4]=[CH:3][C:2]([C:33]#[C:32][CH2:31][NH:34][C:35](=[O:42])[CH2:36][N:37]4[CH2:41][CH2:40][CH2:39][CH2:38]4)=[CH:7]3)=[CH:12][CH:13]=[N:14]2)=[CH:19][CH:18]=1