Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HCID 59327113, 화합물 → Tert-butyl 4-(2-(4-(ethoxycarbonyl)phenoxy)pyridin-3-YL)piperidine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | HCID 59327113 | HCID 59327113 | — |
| 촉매 | Palladium hydroxide | HCID 9942167 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Tert-butyl 4-(2-(4-(ethoxycarbonyl)phenoxy)pyridin-3-YL)piperidine-1-carboxylate | HCID 59326865 | — |
반응 단계
A mixture of tert-butyl 4-(2-(4-(ethoxycarbonyl)phenoxy)pyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate (5.89 g, 13.87 mmol) and palladium hydroxide on carbon (0.950 g, 1.353 mmol) in EtOH (50 mL) was evacuated/purged with hydrogen (1 atm, 3×). After stirring at rt overnight. The mixture was filtered through a pad of Celite and the filtrate was concentrated to dryness to give a light-yellow oil. MS m/z: 427.1 [M+1].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08318718B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-f247155a94ad4058a61b4bf159cec40a |
| 출처 메모 | uspto-grants-2012_11 |