Acetic Acid → 2-Oxopropanal phenylhydrazone

HRID 1880327

반응식

HRID 1880327 반응식
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(O)(=O)C.[CH:13](=O)[C:14]([CH3:16])=[O:15]>O>[C:1]1([NH:7][N:8]=[CH:13][C:14](=[O:15])[CH3:16])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 880MethylglyoxalHCID 7516Phenylhydrazine

생성물 1

HCID 2204342-Oxopropanal phenylhydrazone수율 101.3%

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

To a solution of phenylhydrazine (10.0 g, 92.5 mmol) in water (30 mL) was added acetic acid (8.8 mL) followed by the dropwise addition of pyruvaldehyde (16.7 g, 92.5 mmol) in water (400 mL) over a 15 minute period. The solution was stirred at room temperature overnight. The reaction was filtered and the resultant solid was washed with water (2×30 mL) to provide 2-oxopropanal phenylhydrazone as a yellow solid (15.2 g, 101%).

후처리

  1. filtrationThe reaction was filtered
  2. washthe resultant solid was washed with water (2×30 mL)

출처 및 근거

ORD 기록
ord-99eaab2cecc9412fb4dddd46791e858b
출처 데이터셋
uspto-grants-2012_11
특허 번호
US08318762B2

연결된 노트

불러오는 중…