Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-[1-(Trifluoromethyl)ethenyl]pyridine → 4-(2,2,2-Trifluoro-1-methyl-ethyl)pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-[1-(Trifluoromethyl)ethenyl]pyridine | HCID 59570355 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 4-(2,2,2-Trifluoro-1-methyl-ethyl)pyridine | HCID 59570337 | 85.7% |
반응 단계
To 20 ml of ethyl acetate were added 1.5 g of 4-[1-(trifluoromethyl)ethenyl]pyridine and 0.15 g of 10% Pd/C, and the mixture was stirred under the hydrogen atmosphere for 7 hours. The mixture was filtered, the filtrate was concentrated, and the residue was subjected to silica gel column chromatography to obtain 1.3 g of 4-(2,2,2-trifluoro-1-methyl-ethyl)pyridine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08318776B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-3931ff0361f24cb786007c5b926220fa |
| 출처 메모 | uspto-grants-2012_11 |