Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Nitro-3-phenyl-L-alanine → N-(2,6-Dichlorobenzoyl)-4-nitro-L-phenylalanine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Nitro-3-phenyl-L-alanine | HCID 13706 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2,6-Dichlorobenzoyl chloride | HCID 78392 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | N-(2,6-Dichlorobenzoyl)-4-nitro-L-phenylalanine | HCID 58018322 | — |
반응 단계
Concretely, 4-nitro-L-phenylalanine and 2,6-dichlorobenzoylchloride are condensed in a mixed solvent of a sodium hydroxide aqueous solution and acetone with keeping the reaction temperature at 5 to 15° C., and then crystallization is conducted to obtain a corresponding condensed substance, Nα-(2,6-dichlorobenzoyl)-4-nitro-L-phenylalanine almost quantitatively.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08318975B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-7729fd84b55240708f87f0ec4ff3706d |
| 출처 메모 | uspto-grants-2012_11 |