참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Methyl 2-(2-methoxy-2-oxoethoxy)benzoate | HCID 11287524 | — |
| 생성물 | Benzoic acid, 2-(carboxymethoxy)- | HCID 69461 | 78.2% |
반응 단계
To 10% Solution of Sodium hydroxide (475 mL) was added 2-Methoxycarbonylmethoxy-benzoic acid methyl ester 5 (95 grams, 424 mmol) and heated to 80° C. for 4 hours. Reaction mixture was cooled to room temperature and pH adjusted so 2 with dilute Hydrochloric acid. The crude 80 was purified by dissolving in 10% NaOH and precipitating by acidifying with HCl, to get pure 80 (65 grams, 78.2%) as white powder. M.p: 189-192° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08318973B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_11 |
|---|
| ORD ID | ord-a54d75e8868f418c84fe5470f362eb4c |
|---|
| 출처 메모 | uspto-grants-2012_11 |
|---|
