2-Nitrobenzoyl chloride → N-(6-chloropyridin-3-yl)-2-nitrobenzamide

반응식

[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6](Cl)=[O:7])([O-:3])=[O:2].[NH2:13][C:14]1[CH:15]=[N:16][C:17]([Cl:20])=[CH:18][CH:19]=1>>[Cl:20][C:17]1[N:16]=[CH:15][C:14]([NH:13][C:6](=[O:7])[C:5]2[CH:9]=[CH:10][CH:11]=[CH:12][C:4]=2[N+:1]([O-:3])=[O:2])=[CH:19][CH:18]=1

참가 물질

반응물 2

HCID 118752-Nitrobenzoyl chloride

HCID 793055-Amino-2-chloropyridine

생성물 1

HCID 21906170N-(6-chloropyridin-3-yl)-2-nitrobenzamide

실험 절차

Using methods substantially equivalent to those described in example 1-A, N-(6-chloropyridin-3-yl)-2-nitrob nzamide (1.24 g, 73%) was prepared from 2-nitro-benzoyl chloride and 3-amino-6-chloropyridine.

출처 및 근거

ORD 기록: ord-956187c8628a4baabdce93141f016f76
출처 데이터셋: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06759414B2

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