Imidazole → HCID 13663032, 화합물

반응식

[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.C([O:8][C:9]([C:11]1[NH:12][C:13]2[C:18]([CH:19]=1)=[CH:17][CH:16]=[C:15]([CH3:20])[CH:14]=2)=[O:10])C>>[N:1]1([CH2:20][C:15]2[CH:14]=[C:13]3[C:18]([CH:19]=[C:11]([C:9]([OH:10])=[O:8])[NH:12]3)=[CH:17][CH:16]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

참가 물질

반응물 2

HCID 795Imidazole

HCID 19927845Ethyl 6-methyl-1H-indole-2-carboxylate

생성물 1

HCID 13663032HCID 13663032, 화합물

실험 절차

6-Imidazol-1-ylmethyl-1H-indole-2-carboxylic acid was prepared from imidazole and 6-methyl-1H-indole-2-carboxylic acid ethyl ester using the procedures described by Peter E Cross, et. al; Journal of Medicinal Chemistry 1986, 29(9), 1637-43.

출처 및 근거

ORD 기록: ord-f63baa771c6e442fb37e0a0d2e316f62
출처 데이터셋: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06759428B2

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