Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-[(furan-2-yl)methyl]aniline → N-(furan-2-ylmethyl)-1,3-benzodioxol-5-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-[(furan-2-yl)methyl]aniline | HCID 57541 | — |
| 반응물 | 1-Bromo-3,4-(methylenedioxy)benzene | HCID 75831 | — |
| 생성물 | N-(furan-2-ylmethyl)-1,3-benzodioxol-5-amine | HCID 784117 | 87% |
반응 단계
Using the general procedure, 4-bromo-1,2-(methylenedioxy)benzene (120 μL, 1.0 mmol) was coupled with furfurylaniline (132 μL, 1.5 mmol). Purification of the crude product by column chromatography on silica gel using hexane/ethyl acetate (8:1) as eluent afforded the desired product as a colorless oil (187 mg, 87% yield). Rf=0.5 (hexane/ethyl acetate=5:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06759554B2 |
| 출처 데이터셋 | uspto-grants-2004_07 |
| ORD ID | ord-2e2fa03f72ab4712aff192d23789471c |
| 출처 메모 | uspto-grants-2004_07 |