Methyl malonyl chloride → HCID 9997061, 화합물

HRID 1884109노트

반응식

HRID 1884109 반응식
[F:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[CH:11]=2)[CH:5]=[CH:4][C:3]=1[NH2:17].[CH3:18][O:19][C:20](=[O:25])[CH2:21][C:22](Cl)=[O:23]>>[CH3:18][O:19][C:20](=[O:25])[CH2:21][C:22]([NH:17][C:3]1[CH:4]=[CH:5][C:6]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[CH:11]=2)=[CH:7][C:2]=1[F:1])=[O:23]

참가 물질

3

반응물 2

HCID 123460Methyl malonyl chlorideHCID 21920051HCID 21920051, 화합물

생성물 1

HCID 9997061HCID 9997061, 화합물수율 47%

실험 절차

In analogy to example 1, the title compound is prepared from 2-fluoro-4-(3-fluoro-benzyloxy)-phenylamine and chlorocarbonyl-acetic acid methyl ester. Yield: 47%. Brownish solid. MS: m/e=336.1 (M++H).

출처 및 근거

ORD 기록
ord-ade181a53b1c43bbbdfa58ec49413faf
출처 데이터셋
uspto-grants-2004_07
특허 번호
US06762320B2

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