참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzoic Acid | HCID 243 | — |
| 반응물 | Ethylbenzene | HCID 7500 | — |
| 반응물 | 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl acetate | HCID 265566 | — |
| 촉매 | Cobalt(II) acetate tetrahydrate | HCID 61372 | — |
| 촉매 | Manganese acetate tetrahydrate | HCID 93021 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | Acetophenone | HCID 7410 | 85% |
반응 단계
A mixture of 1.062 g (10 mmol) of ethylbenzene, 0.205 g (1 mmol) of N-acetoxyphthalimide, 0.025 g (0.1 mmol) of cobalt(II) acetate tetrahydrate, 0.025 g (0.1 mmol) of manganese(II) acetate tetrahydrate and 15 ml of acetic acid was stirred at 130° C. in an atmosphere of air [2 MPa (gauge pressure)] for 8 hours and thereby yielded benzoic acid in a yield of 85% (analyzed by gas chromatography) with a conversion from ethylbenzene of 96%. In this procedure, acetophenone was not produced.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07741514B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_06 |
|---|
| ORD ID | ord-0ed1deefb693476d8324060234940cbd |
|---|
| 출처 메모 | uspto-grants-2010_06 |
|---|
