Quinoxalin-6-ylmethanol → Quinoxaline-6-carboxaldehyde

HRID 1886339

반응식

HRID 1886339 반응식
[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH2:11][OH:12])=[CH:8][CH:9]=2)[N:4]=[CH:3][CH:2]=1>[O-2].[Mn+4].[O-2].ClCCl>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]=[O:12])=[CH:8][CH:9]=2)[N:4]=[CH:3][CH:2]=1

참가 물질

4

반응물 1

HCID 6422829Quinoxalin-6-ylmethanol

생성물 1

HCID 763958Quinoxaline-6-carboxaldehyde수율 67.3%

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 6344Dichloromethane용매

실험 절차

To a stirred solution of 10 parts of intermediate 5, namely 6-quinoxalinemethanol in 133 parts of dichloromethane were added 20 parts of manganese(IV) oxide. After stirring for 3 hours at room temperature, the reaction mixture was filtered and the filtrate was evaporated, yielding 6.6 parts (67.3%) of 6-quinoxalinecarboxaldehyde; mp. 134° C. (interm. 6).

후처리

  1. filtrationthe reaction mixture was filtered
  2. customthe filtrate was evaporated

출처 및 근거

ORD 기록
ord-f4b0bf20122f46e99cbe24fc4184fb9d
출처 데이터셋
uspto-grants-1992_09
특허 번호
US05151421

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