Trifluoroacetic acid → 2-(12-Phthalimido dodecyl)propane dioic acid

HRID 1886746노트

반응식

HRID 1886746 반응식
C([O:5][C:6](=[O:38])[CH:7]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][N:27]1[C:31](=[O:32])[C:30]2=[CH:33][CH:34]=[CH:35][CH:36]=[C:29]2[C:28]1=[O:37])[C:8]([O:10]C(C)(C)C)=[O:9])(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[C:28]1(=[O:37])[N:27]([CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH:7]([C:6]([OH:38])=[O:5])[C:8]([OH:10])=[O:9])[C:31](=[O:32])[C:30]2=[CH:33][CH:34]=[CH:35][CH:36]=[C:29]12

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 866489122-(12-Phthalimido dodecyl)propane dioic acid di-tert-butyl ester

생성물 1

HCID 866489112-(12-Phthalimido dodecyl)propane dioic acid수율 100%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Following general procedure D, 16.0 mmol (8.45 g) of 5c and 160 mmol (11.9 mL) of trifluoroacetic acid were reacted in 12 mL of dichloromethane at room temperature and the mixture was processed. Yield 100%.

출처 및 근거

ORD 기록
ord-2c5e79c602a84d9fa0caec80d5c30337
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08501199B2

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