Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenyl isocyanate → 1-Phenyl-3-(2-phenylbenzo[d]oxazol-5-yl)urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenyl isocyanate | HCID 7672 | — |
| 반응물 | 2-Phenyl-1,3-benzoxazol-5-amine | HCID 721059 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-Phenyl-3-(2-phenylbenzo[d]oxazol-5-yl)urea | HCID 67332508 | 85% |
반응 단계
To 2-phenylbenzo[d]oxazol-5-amine (75 mg, 0.36 mmol) in dichloromethane (2 mL) at room temperature was added phenyl isocyanate (43 μL, 0.39 mmol). The solution was stirred at room temperature for 16 h. The resulting precipitate was filtered off and washed with dichloromethane to afford 99.9 mg (85%) of the title compound (LCMS RT=6.45 min, MH+ 330.1)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08501713B2 |
| 출처 데이터셋 | uspto-grants-2013_08 |
| ORD ID | ord-c3b535fff2704f91b0ee1b438bd2f08f |
| 출처 메모 | uspto-grants-2013_08 |