2-(Morpholin-4-yl)isonicotinic acid → N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-morpholin-4-yl-isonicotinamide

HRID 1887832

반응식

HRID 1887832 반응식
[NH2:1][CH2:2][C:3]1[C:12](=[O:13])[C:11]2[C:6](=[CH:7][C:8]([Cl:14])=[CH:9][CH:10]=2)[N:5]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:4]=1[C:21]1[O:22][CH:23]=[CH:24][N:25]=1.[O:26]1[CH2:31][CH2:30][N:29]([C:32]2[CH:33]=[C:34]([CH:38]=[CH:39][N:40]=2)[C:35](O)=[O:36])[CH2:28][CH2:27]1>>[Cl:14][C:8]1[CH:7]=[C:6]2[C:11]([C:12](=[O:13])[C:3]([CH2:2][NH:1][C:35](=[O:36])[C:34]3[CH:38]=[CH:39][N:40]=[C:32]([N:29]4[CH2:28][CH2:27][O:26][CH2:31][CH2:30]4)[CH:33]=3)=[C:4]([C:21]3[O:22][CH:23]=[CH:24][N:25]=3)[N:5]2[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:10][CH:9]=1

참가 물질

3

반응물 2

HCID 27624792-(Morpholin-4-yl)isonicotinic acidHCID 712083323-aminomethyl-7-chloro-2-oxazol-2-yl-1-phenyl-1H-quinolin-4-one

생성물 1

HCID 71208898N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-morpholin-4-yl-isonicotinamide

실험 절차

N-(7-Chloro-2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-morpholin-4-yl-isonicotinamide was prepared starting from intermediate A and 2-morpholinoisonicotinic acid. MS calcd. for C29H25ClN5O4 [(M+H)+] 542.2, obsd. 542.2.

출처 및 근거

ORD 기록
ord-8395b00111c041749fd1fb794bb85207
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08501732B2

연결된 노트

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