Pyridine-4-carbonyl chloride → 7-Chloro-4-oxo-1-phenyl-3-{[(pyridine-4-carbonyl)-amino]-methyl}-1,4-dihydro-quinoline-2-carboxylic acid methyl ester
반응식
Cl.[CH3:2][O:3][C:4]([C:6]1[N:7]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:8]2[C:13]([C:14](=[O:18])[C:15]=1[CH2:16][NH2:17])=[CH:12][CH:11]=[C:10]([Cl:19])[CH:9]=2)=[O:5].[C:26](Cl)(=[O:33])[C:27]1[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=1>>[CH3:2][O:3][C:4]([C:6]1[N:7]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:8]2[C:13]([C:14](=[O:18])[C:15]=1[CH2:16][NH:17][C:26]([C:27]1[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=1)=[O:33])=[CH:12][CH:11]=[C:10]([Cl:19])[CH:9]=2)=[O:5]참가 물질
3
실험 절차
7-Chloro-4-oxo-1-phenyl-3-{[(pyridine-4-carbonyl)-amino]-methyl}-1,4-dihydro-quinoline-2-carboxylic acid methyl ester was prepared starting from intermediate I and isonicotinoyl chloride. MS calcd. for C24H19ClN3O4 [(M+H)+] 448.1, obsd. 447.9.
출처 및 근거
- ORD 기록
- ord-7b41067ca76a4d0f931626498ff41e88