Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → HCID 178477702, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Ethanesulfonyl chloride | HCID 11667 | — |
| 반응물 | HCID 178479542 | HCID 178479542 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 178477702 | HCID 178477702 | — |
반응 단계
This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus, 3-(4-piperidinyl)-5-(3-thienyl)-1H-indazole-7-carboxamide hydrochloride (Intermediate 19) (0.117 mmol) was reacted with ethane sulfonyl chloride (0.02 mL, 0.234 mmol) in the presence of triethylamine (0.04 mL, 0.468 mmol) in methylene chloride (10 mL) to give the title compound (9.4 mg, 19% for the last two steps)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08501780B2 |
| 출처 데이터셋 | uspto-grants-2013_08 |
| ORD ID | ord-8d288bc1b3644834885618bae5388d28 |
| 출처 메모 | uspto-grants-2013_08 |