Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → HCID 178477699, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Ethanesulfonyl chloride | HCID 11667 | — |
| 반응물 | HCID 178479540 | HCID 178479540 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 178477699 | HCID 178477699 | — |
반응 단계
This compound was prepared in a fashion analogous to the procedure described in Example 3. Thus 3-(4-piperidinyl)-5-(3-pyridinyl)-1H-indazole-7-carboxamide hydrochloride (Intermediate 21) (0.09 mmol) was reacted with ethane sulfonyl chloride (0.01 mL, 0.217 mmol) in the presence of triethylamine (0.04 mL, 0.468 mmol) in methylene chloride (10 mL) to give the title compound (4.9 mg, 13% for the last two steps)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08501780B2 |
| 출처 데이터셋 | uspto-grants-2013_08 |
| ORD ID | ord-06aebaefeaeb4ed088fcd0e4819e3401 |
| 출처 메모 | uspto-grants-2013_08 |