Ornoprostil → HCID 10927388, 화합물

HRID 1888303

반응식

[OH:1][C@@H:2]1[CH2:6][C:5](=[O:7])[C@H:4]([CH2:8][C:9](=[O:18])[CH2:10][CH2:11][CH2:12][CH2:13][C:14]([O:16]C)=[O:15])[C@H:3]1/[CH:19]=[CH:20]/[C@@H:21]([OH:29])[CH2:22][C@@H:23]([CH3:28])[CH2:24][CH2:25][CH2:26][CH3:27].O[C@@H](C[C@@H](C)CCCC)/C=C/[C@H]1CCC(=O)[C@@H]1CCSC1SC=C(C(OCC)=O)N=1>>[OH:1][C@@H:2]1[CH2:6][C:5](=[O:7])[C@H:4]([CH2:8][C:9](=[O:18])[CH2:10][CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15])[C@H:3]1/[CH:19]=[CH:20]/[C@@H:21]([OH:29])[CH2:22][C@@H:23]([CH3:28])[CH2:24][CH2:25][CH2:26][CH3:27]

참가 물질

반응물 2

HCID 5282205Ornoprostil

HCID 66858273HCID 66858273, 화합물

생성물 1

HCID 10927388HCID 10927388, 화합물

실험 절차

By the same procedure as the reaction of Example 30 using methyl 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}-6-oxoheptanoate (Reg No.70667-26-4) instead of the compound 29, the title compound having the following physical data was obtained.

출처 및 근거

ORD 기록: ord-0e96babb74274fc5b0b6d8f4613c210f
출처 데이터셋: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08501793B2

연결된 노트

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