Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ornoprostil → 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}-6-oxoheptanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ornoprostil | HCID 5282205 | — |
| 반응물 | ethyl 2-[(2-{(1R,2R)-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}ethyl)thio]-1,3-thiazole-4-carboxylate | HCID 66858273 | — |
| 생성물 | 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}-6-oxoheptanoic acid | HCID 10927388 | — |
반응 단계
By the same procedure as the reaction of Example 30 using methyl 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl}-6-oxoheptanoate (Reg No.70667-26-4) instead of the compound 29, the title compound having the following physical data was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08501793B2 |
| 출처 데이터셋 | uspto-grants-2013_08 |
| ORD ID | ord-0e96babb74274fc5b0b6d8f4613c210f |
| 출처 메모 | uspto-grants-2013_08 |