Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → HCID 178441303, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid | HCID 21491 | — |
| 반응물 | 2-tert-Butyl-4-butylisothiazol-5(2H)-imine | HCID 66867228 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 178441303 | HCID 178441303 | — |
반응 단계
The product from Example 92B and the (+) camphoric acid (Aldrich) were processed using the method described in Example 170 except that the methanol used to trap the intermediate was saturated with ammonia solution instead of methanol to afford the title compound. 1H NMR (DMSO-d6) δ 0.50 (s, 3H), 0.90 (t, J=7.2 Hz, 3H), 1.19 (s, 3H), 1.23-1.44 (m, 3H), 1.26 (s, 3H), 1.57 (s, 9H), 1.57-1.71 (m, 3H), 1.93-2.06 (m, 1H), 2.71-2.82 (m, 1H), 2.62-2.69 (m, 3H), 7.01 (s, 1H), 6.75 (s, 1H), 8.50 (s, 1H). MS (ESI+) m/z 394 (M+H)+. Anal. calcd. for C11H35N3O2S: C, 64.08; H, 8.96; N, 10.68. Found: C, 64.26; H, 9.10; N, 10.65.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08501794B2 |
| 출처 데이터셋 | uspto-grants-2013_08 |
| ORD ID | ord-a7405d8924b6428ca7d618916c83d8e4 |
| 출처 메모 | uspto-grants-2013_08 |