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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1890243생성일: 2026년 10월 25일

4-Chloro-o-anisic acid → (+/-)-4-Fluoro-2-methoxy-N-(4-oxo-2-pyridin-4-yl-5,6,8,9-tetrahydro-4H-7-oxa-1,4a-diaza-benzocyclohepten-9-yl)-benzamide

https://huagongshe.com/reaction/1890243

반응식

참여 물질

역할이름HCID투입량
반응물4-Chloro-o-anisic acidHCID 93682—
반응물4-Fluoro-2-methoxybenzoic acidHCID 2774545—
반응물(+/-) 9-Amino-2-pyridin-4-yl-5,6,8,9-tetrahydro-7-oxa-1,4a-diaza-benzocyclohepten-4-oneHCID 66846193—
생성물(+/-)-4-Fluoro-2-methoxy-N-(4-oxo-2-pyridin-4-yl-5,6,8,9-tetrahydro-4H-7-oxa-1,4a-diaza-benzocyclohepten-9-yl)-benzamideHCID 44159612—

반응 단계

By analogy with the method described in example 1 (step 1.4), using (+/−) 9-amino-2-pyridin-4-yl-5,6,8,9-tetrahydro-7-oxa-1,4a-diaza-benzocyclohepten-4-one and 4-fluoro-2-methoxy benzoic acid in place of (+/−)-9-amino-2-pyrimidin-4-yl-5,6,8,9-tetrahydro-7-oxa-1,4a-diaza-benzocyclohepten-4-one and 4-chloro-2-methoxy-benzoic acid, the compound, 0.068 g (71%), was obtained as a powder.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08507470B2
출처 데이터셋uspto-grants-2013_08
ORD IDord-7bd987bb57674e3292dae1f2be6e633d
출처 메모uspto-grants-2013_08