1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, methyl ester → {1H-pyrrolo[3,2-b]pyridin-2-yl}methanamine

HRID 1890536노트

반응식

HRID 1890536 반응식
[NH:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[C:10](OC)=O.[NH:14]1C2=NC=CC=C2C=C1CN>>[NH:1]1[C:9]2[C:4](=[N:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[C:2]1[CH2:10][NH2:14]

참가 물질

3

반응물 2

HCID 222817761H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, methyl esterHCID 67305381(1H-Pyrrolo[2,3-b]pyridin-2-yl)methanamine

생성물 1

HCID 46856478{1H-pyrrolo[3,2-b]pyridin-2-yl}methanamine

실험 절차

Intermediate I was prepared from methyl 1H-pyrrolo[3,2-b]pyridine-2-carboxylate (1-1) following similar procedures for synthesizing intermediate H, as described above. MS (m/z): 148 (M+1)+.

출처 및 근거

ORD 기록
ord-b5b2e4ce1b0d47acbf24a609ac2f8725
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08507487B2

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