Pyrazolo[1,5-a]pyriMidine-5-carbonitrile → Pyrazolo[1,5-a]pyrimidine-5-methanamine

HRID 1890543노트

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HRID 1890543 반응식
[N:1]1[N:5]2[CH:6]=[CH:7][C:8]([C:10]#[N:11])=[N:9][C:4]2=[CH:3][CH:2]=1.S1C2=NC=CC=C2C(CN)=C1>>[N:1]1[N:5]2[CH:6]=[CH:7][C:8]([CH2:10][NH2:11])=[N:9][C:4]2=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 23156341Pyrazolo[1,5-a]pyriMidine-5-carbonitrileHCID 67305656HCID 67305656, 화합물

생성물 1

HCID 67305688Pyrazolo[1,5-a]pyrimidine-5-methanamine

실험 절차

Intermediate M was prepared from pyrazolo[1,5-a]pyrimidine-5-carbonitrile (M−1) following similar procedures for synthesizing intermediate J from J-4, as described above. MS (m/z): 149 (M+1)+.

출처 및 근거

ORD 기록
ord-2da9cccbfffd499685022ab4a34ba005
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08507487B2

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