Imidazo(1,2-b)pyridazine → HCID 58190513, 화합물

HRID 1892375

반응식

HRID 1892375 반응식
[F:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[N:7][N:8]2[CH3:11])=[CH:4][C:3]=1[CH:12]([C:14]1[N:18]2[N:19]=[C:20]([C:23](=[O:25])[CH3:24])[CH:21]=[CH:22][C:17]2=[N:16][CH:15]=1)C.N1C=CN2C=1C=CC=N2>>[F:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[N:7][N:8]2[CH3:11])=[CH:4][C:3]=1[CH2:12][C:14]1[N:18]2[N:19]=[C:20]([C:23](=[O:25])[CH3:24])[CH:21]=[CH:22][C:17]2=[N:16][CH:15]=1

참가 물질

3

반응물 2

HCID 136599Imidazo(1,2-b)pyridazineHCID 581905981-(3-(1-(6-Fluoro-1-methyl-1H-indazol-5-yl)ethyl)imidazo[1,2-b]pyridazin-6-yl)ethanone

생성물 1

HCID 58190513HCID 58190513, 화합물

실험 절차

The title compound was prepared as a white solid in analogy to the synthesis of compound 39.4 from 6-(1-ethoxyvinyl)-3-(6-fluoro-1-methyl-1H-indazol-5-yl)methyl)imidazo[1,2-b]pyridazine. LCMS (method B): [MH]+=324, tR=2.41 min.

출처 및 근거

ORD 기록
ord-5ced46ca6da442c5b3157aa5bd0f1315
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08507676B2

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