Methyl 4-bromobenzoate → Methyl 4-(4-oxobutyl)benzoate

반응식

Br[C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][CH:3]=1.[CH2:12]([OH:16])[CH2:13][CH:14]=[CH2:15]>>[C:6]([C:5]1[CH:10]=[CH:11][C:2]([CH2:15][CH2:14][CH2:13][CH:12]=[O:16])=[CH:3][CH:4]=1)([O:8][CH3:9])=[O:7]

참가 물질

반응물 2

HCID 12081Methyl 4-bromobenzoate

HCID 693893-Buten-1-ol

생성물 1

HCID 9859111Methyl 4-(4-oxobutyl)benzoate

실험 절차

condensing methyl p-bromobenzoate with 3-buten-1-ol; extracting the reaction mixture with an organic solvent to obtain an organic extract; decolorizing the organic extract with silica gel, and then removing the organic solvent to give 4-(4-carbomethoxyphenyl) butanal.

후처리

extractionextracting the reaction mixture with an organic solvent
customto obtain an organic extract
extractionorganic extract with silica gel
customremoving the organic solvent

출처 및 근거

ORD 기록: ord-64426e8617f04b7c9ad514159d276864
출처 데이터셋: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08507716B2

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