4-Amino-1-methylcyclohexanol hydrochloride → HCID 66884089, 화합물

HRID 1893396노트

반응식

HRID 1893396 반응식
[Br:1][C:2]1[C:3]([O:9][C@@H:10]2[CH2:14][CH2:13][O:12][CH2:11]2)=[N:4][C:5](Cl)=[N:6][CH:7]=1.Cl.[NH2:16][CH:17]1[CH2:22][CH2:21][C:20]([CH3:24])([OH:23])[CH2:19][CH2:18]1>>[O:12]1[CH2:13][CH2:14][C@@H:10]([O:9][C:3]2[C:2]([Br:1])=[CH:7][N:6]=[C:5]([NH:16][CH:17]3[CH2:22][CH2:21][C:20]([CH3:24])([OH:23])[CH2:19][CH2:18]3)[N:4]=2)[CH2:11]1

참가 물질

3

반응물 2

HCID 218771344-Amino-1-methylcyclohexanol hydrochlorideHCID 58515275HCID 58515275, 화합물

생성물 1

HCID 66884089HCID 66884089, 화합물

실험 절차

Using the procedure of Example 78, Step 2, (R)-5-bromo-2-chloro-4-(tetrahydrofuran-3-yloxy)pyrimidine was reacted with 4-amino-1-methylcyclohexanol HCl salt to provide the title compound. MS (ESI) m/z: Found: 372 (M++1), Calc. 371 (M+).

출처 및 근거

ORD 기록
ord-4f78bd80ad1841af85dea98aff5919ca
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08513242B2

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