Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) → HCID 66881356, 화합물

반응식

[CH2:1]([O:3][C:4](=[O:25])[CH2:5][N:6]([CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[C:7]1[CH:15]=[C:14]2[C:10]([C:11]([CH2:16][CH3:17])=[N:12][NH:13]2)=[CH:9][C:8]=1[CH3:18])[CH3:2].F[B-](F)(F)F.[CH3:31][O+](C)C>>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][N:6]([CH2:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])[C:7]1[C:8]([CH3:18])=[CH:9][C:10]2[C:14]([CH:15]=1)=[N:13][N:12]([CH3:31])[C:11]=2[CH2:16][CH3:17])[CH3:2]

참가 물질

반응물 2

HCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)

HCID 178472736HCID 178472736, 화합물

생성물 1

HCID 66881356HCID 66881356, 화합물수율 33%

실험 절차

Using the compound (722 mg, 2.08 mmol) of step C, and trimethyloxonium tetrafluoroborate (527 mg, 3.56 mmol), and according to the method of Reference Example 137, step F, the title compound (248 mg, yield 33%) was obtained as a yellow oil.

출처 및 근거

ORD 기록: ord-ae80183453ac4c868396c9f71913778e
출처 데이터셋: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08513235B2

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