Dichloromethane → (+/-)-N-{2-[1-(3-benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-2-methyl-propylamino]-1,1-dimethyl-ethyl}-3-fluoro-4-methyl-benzamide

HRID 189432노트

반응식

[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cl:48][CH2:49][Cl:50].[F:37][c:38]1[cH:39][c:40]([C:41](=[O:42])[Cl:43])[cH:44][cH:45][c:46]1[CH3:47].[NH2:1][C:2]([CH2:3][NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[c:9]1[n:10][c:11]2[cH:12][c:13]([Cl:27])[cH:14][cH:15][c:16]2[c:17](=[O:26])[n:18]1[CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)([CH3:28])[CH3:29]>>[NH:1]([C:2]([CH2:3][NH:4][CH:5]([CH:6]([CH3:7])[CH3:8])[c:9]1[n:10][c:11]2[cH:12][c:13]([Cl:27])[cH:14][cH:15][c:16]2[c:17](=[O:26])[n:18]1[CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)([CH3:28])[CH3:29])[C:41]([c:40]1[cH:39][c:38]([F:37])[c:46]([CH3:47])[cH:45][cH:44]1)=[O:42]