Nitromethane → HCID 57743020, 화합물

HRID 1896360노트

반응식

HRID 1896360 반응식
[F:1][C:2]1[C:7]([F:8])=[CH:6][C:5]([F:9])=[CH:4][C:3]=1[CH:10]=[CH:11][C:12]([O:14]CC)=O.[N+:17]([CH3:20])([O-])=O>>[F:1][C:2]1[C:7]([F:8])=[CH:6][C:5]([F:9])=[CH:4][C:3]=1[CH:10]1[CH2:20][NH:17][C:12](=[O:14])[CH2:11]1

참가 물질

3

반응물 2

HCID 6375NitromethaneHCID 86631463HCID 86631463, 화합물

생성물 1

HCID 57743020HCID 57743020, 화합물

실험 절차

4-(2,3,5-trifluorophenyl)pyrrolidin-2-one x38 is synthesized from nitromethane and ethyl 3-(2,3,5-trifluorophenyl)acrylate according to the methodology described in Kenda B. et al., J. Med. Chem. (2004), 47, 530-549.

출처 및 근거

ORD 기록
ord-97733bd11b584f4d97e07abc16b6f16a
출처 데이터셋
uspto-grants-2013_08
특허 번호
US08518943B2

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