7-Bromo-1-[(4-methoxybenzyl)amino][1]benzothieno[3,2-c]pyridine-4-carbonitrile → HCID 59198443, 화합물
반응식
Br[C:2]1[CH:7]=[CH:6][C:5]2[C:8]3[C:9]([NH:17][CH2:18][C:19]4[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=4)=[N:10][CH:11]=[C:12]([C:15]#[N:16])[C:13]=3[S:14][C:4]=2[CH:3]=1.Cl.[CH3:28][N:29]([CH2:31][C:32]1[CH:37]=[CH:36][C:35](B(O)O)=[CH:34][CH:33]=1)[CH3:30]>>[CH3:28][N:29]([CH2:31][C:32]1[CH:37]=[CH:36][C:35]([C:2]2[CH:7]=[CH:6][C:5]3[C:8]4[C:9]([NH:17][CH2:18][C:19]5[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=5)=[N:10][CH:11]=[C:12]([C:15]#[N:16])[C:13]=4[S:14][C:4]=3[CH:3]=2)=[CH:34][CH:33]=1)[CH3:30]참가 물질
3
실험 절차
The title compound was prepared by the method described in Example 19, Step 1 using 7-bromo-1-[(4-methoxybenzyl)amino][1]benzothieno[3,2-c]pyridine-4-carbonitrile Example 12, Steep 9) and {4-[(dimethylamino)methyl]phenyl}boronic acid hydrochloride.
출처 및 근거
- ORD 기록
- ord-a006541ef9e84cec891bb3fc66b37dfe
- 출처 데이터셋
- uspto-grants-2013_08