참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Bromobenzyl bromide | HCID 69979 | — |
| 반응물 | tert-butyl N-(3-hydroxyphenyl)carbamate | HCID 312485 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Tert-butyl 3-(3-bromobenzyloxy)phenylcarbamate | HCID 59418705 | — |
반응 단계
To tert-butyl 3-hydroxyphenylcarbamate (0.245 g, 1.17 mmol), K2CO3 (404 mg, 2.93 mmol), and 3-bromobenzyl bromide (322 mg, 1.29 mmol) was added anhydrous DMF (5 mL). The reaction mixture was heated to 60° C. for 18 hours. The reaction mixture was cooled to rt, poured into water and the resulting precipitate was collected by filtration and washed with water to provide the desired product tert-butyl 3-(3-bromobenzyloxy)phenylcarbamate (34A) with sufficient purity for subsequent use.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08518970B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_08 |
|---|
| ORD ID | ord-94bb1667a57f46eb981a0628217bd1d1 |
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| 출처 메모 | uspto-grants-2013_08 |
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