3-Morpholinopropane-1-sulfonyl chloride → 5-[2-Ethoxy-5-(3-morpholinopropylsulphonamido)phenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

반응식

[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:22][CH2:23][CH3:24])[c:6](-[c:8]2[nH:9][c:10](=[O:21])[c:11]3[c:12]([n:13]2)[c:14]([CH2:18][CH2:19][CH3:20])[n:15][n:16]3[CH3:17])[cH:7]1.[O:25]1[CH2:26][CH2:27][N:28]([CH2:31][CH2:32][CH2:33][S:34](=[O:35])(=[O:36])[Cl:37])[CH2:29][CH2:30]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([O:22][CH2:23][CH3:24])[c:6](-[c:8]2[nH:9][c:10](=[O:21])[c:11]3[c:12]([n:13]2)[c:14]([CH2:18][CH2:19][CH3:20])[n:15][n:16]3[CH3:17])[cH:7]1)[S:34]([CH2:33][CH2:32][CH2:31][N:28]1[CH2:27][CH2:26][O:25][CH2:30][CH2:29]1)(=[O:35])=[O:36]

참가 물질

반응물 2

HCID 219731893-Morpholinopropane-1-sulfonyl chloride

HCID 1357385605-(5-Amino-2-ethoxyphenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

생성물 1

HCID 1357385385-[2-Ethoxy-5-(3-morpholinopropylsulphonamido)phenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

출처 및 근거

ORD 기록: ord-d02cb9d7d2d94cbdb6fae6ec06b97f1a
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

반응 노트

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