Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 1-Isopropyl-2-oxo-1,2-dihydro-3-quinolinecarboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Ethyl 1-isopropyl-2-oxo-1,2-dihydro-3-quinolinecarboxylate | HCID 15468682 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-Isopropyl-2-oxo-1,2-dihydro-3-quinolinecarboxylic acid | HCID 10944290 | 88.3% |
반응 단계
A solution of 1.55 g of ethyl 1-isopropyl-2(1H)-quinolone-3-carboxylate and 0.28 g of sodium hydroxide in a mixture of 10 ml of ethanol and 2 ml of water was stirred overnight at room temperature. After the solvent was distilled off, dil. hydrochloric acid was added to the residue. The precipitated solid was taken by filtration, washed with water and dried to give 1.22 g of 1-isopropyl-2(1H)-quinolone-3-carboxylic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05571820 |
| 출처 데이터셋 | uspto-grants-1996_11 |
| ORD ID | ord-517c823989d348d195c3c138d15bd565 |
| 출처 메모 | uspto-grants-1996_11 |