Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfisoxazole → 1-Cyclohexyl-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfisoxazole | HCID 5344 | — |
| 반응물 | Cyclohexyl isocyanate | HCID 18502 | — |
| 생성물 | 1-Cyclohexyl-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea | HCID 4054520 | — |
반응 단계
This compound was prepared from 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzene-sulfonamide and cyclohexyl isocyanate according to the method in Example 110 in 75% crude yield. Further purification was achieved by preparative HPLC (76% recovery), furnishing the pure product as a white solid, m.p. 190°-195° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05571821 |
| 출처 데이터셋 | uspto-grants-1996_11 |
| ORD ID | ord-038f879dac3c45869fa859d2befa14a5 |
| 출처 메모 | uspto-grants-1996_11 |