2-(Piperazin-1-yl)pyridine-3-carbonitrile → 2-[4-(1H-thieno[3,4-d]imidazol-2-ylmethyl)piperazin-1-yl]pyridine-3-carbonitrile

반응식

[Cl:1][CH2:2][c:3]1[n:4][c:5]2[c:6]([nH:7]1)[cH:8][s:9][cH:10]2.[N:11]1([c:17]2[c:18]([C:19]#[N:20])[cH:21][cH:22][cH:23][n:24]2)[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1>>[CH2:2]([c:3]1[nH:4][c:5]2[c:6]([n:7]1)[cH:8][s:9][cH:10]2)[N:14]1[CH2:13][CH2:12][N:11]([c:17]2[c:18]([C:19]#[N:20])[cH:21][cH:22][cH:23][n:24]2)[CH2:16][CH2:15]1

참가 물질

반응물 2

HCID 27372032-(Piperazin-1-yl)pyridine-3-carbonitrile

HCID 220659962-(chloromethyl)-1H-thieno[3,4-d]imidazole

생성물 1

HCID 99963732-[4-(1H-thieno[3,4-d]imidazol-2-ylmethyl)piperazin-1-yl]pyridine-3-carbonitrile

출처 및 근거

ORD 기록: ord-af103e1c72d24efbb00b8509cf8ab99e
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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