Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzene → 2-{2-[3,4-Bis(methoxycarbonyl)phenoxy]-1-methylethyl}amino-1-(3-chlorophenyl)ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzene | HCID 241 | — |
| 반응물 | 2-Amino-1-(3-chlorophenyl)ethan-1-ol | HCID 3751601 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | Dimethyl 4-(2-oxopropoxy)phthalate | HCID 21832192 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-{2-[3,4-Bis(methoxycarbonyl)phenoxy]-1-methylethyl}amino-1-(3-chlorophenyl)ethanol | HCID 21832161 | — |
반응 단계
Following a procedure similar to that described in Example 6, but using 2 g of 2-amino-1-(3-chlorophenyl)ethanol (prepared as described in Preparation 8), 3.73 g of dimethyl 4-(2-oxopropoxy)phthalate (prepared as described in Preparation 54), 70 ml of benzene, 60 ml of absolute methanol and 1.32 g of sodium borohydride, the title compound was obtained having an Rf=0.29 (thin layer chromatography over silica gel, using ethyl acetate as the developing solvent).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05576340 |
| 출처 데이터셋 | uspto-grants-1996_11 |
| ORD ID | ord-6ff981c6a7db4b8b883db5377fd61819 |
| 출처 메모 | uspto-grants-1996_11 |