Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 1-Azido-3-phenylpropan-2-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Methyl formate | HCID 7865 | — |
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | 2-(Phenylmethyl)oxirane | HCID 94826 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-Azido-3-phenylpropan-2-ol | HCID 13764832 | 91.3% |
반응 단계
A procedure similar to that described in Preparation 12 was repeated, except that 5 g of (±)-(2,3-epoxypropyl)benzene, 12.1 g of sodium azide, 60 ml of methyl formate and 270 ml of an 8:1 by volume mixture of methanol and water were used, to give 6.03 g of the title compound as a colorless oil having an Rf value of 0.3 (on silica gel thin layer chromatography, using a 1:4 by volume mixture of ethyl acetate and hexane as the developing solvent).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05578620 |
| 출처 데이터셋 | uspto-grants-1996_11 |
| ORD ID | ord-e16746bc14314472b859c2c29b2239bf |
| 출처 메모 | uspto-grants-1996_11 |