Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 3-(8-Phenyloctyloxy)-2-hydroxypropylazide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Methyl formate | HCID 7865 | — |
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | 8-Phenyloctyloxymethyloxirane | HCID 21474710 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-(8-Phenyloctyloxy)-2-hydroxypropylazide | HCID 21474713 | 96.7% |
반응 단계
A procedure similar to that described in Preparation 12 was repeated, except that 2.4 g of 8-phenyloctyloxymethyloxirane (prepared as described in Preparation 64), 2.97 g of sodium azide, 20 ml of methyl formate and 80 ml of an 8:1 by volume mixture of methanol and water were used, to give 2.7 g of the title compound having an Rf value of 0.29 (on silica gel thin layer chromatography, using a 1:5 by volume mixture of ethyl acetate and hexane as the developing solvent).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05578620 |
| 출처 데이터셋 | uspto-grants-1996_11 |
| ORD ID | ord-62bf5ae3e93a4b91900b6802c7cca1e7 |
| 출처 메모 | uspto-grants-1996_11 |