Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boron tribromide → HCID 23368791, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boron tribromide | HCID 25134 | — |
| 반응물 | 1-(4-Chlorobenzyl)-5-methoxy-2-methylindole-3-acetic acid | HCID 4059895 | — |
| 반응물 | 1-[(4-Chlorophenyl)methyl]-5-hydroxy-2-methyl-1H-indole-3-acetic acid methyl ester | HCID 53817482 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 23368791 | HCID 23368791 | — |
반응 단계
1-[(4-Chlorophenyl)methyl]-5-hydroxy-2-methyl-1H-indole-3-acetic acid methyl ester. Using the methods in Example 63, Part C, 1.2 g (3.5 mmol) of 1-[(4-chlorophenyl)methyl]-5-methoxy-2-methyl-1H-indole-3-acetic acid was treated with 15 mL of 1M BBr3 in CH2Cl2 to give crude 1-[(4-chlorophenyl)-methyl]-5-hydroxy-2-methyl-1H-indole-3-acetic acid which was treated with sulfuric acid in MeOH to give 1.2 g of 1-[(4-chlorophenyl)methyl]-5-hydroxy-2-methyl-1H-indole-3-acetic acid methyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05578634 |
| 출처 데이터셋 | uspto-grants-1996_11 |
| ORD ID | ord-3236222f72e941c788dc77e1abfa8ce4 |
| 출처 메모 | uspto-grants-1996_11 |