2-Nitrobenzyl chloride → 2-[(2-nitrophenyl)methyl]isoindole-1,3-dione

HRID 1902191

반응식

HRID 1902191 반응식
[CH:1]1[CH:6]=[C:5]2[C:7]([N-:9][C:10](=[O:11])[C:4]2=[CH:3][CH:2]=1)=[O:8].[K+].[N+:13]([C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18]Cl)([O-:15])=[O:14]>CN(C)C=O>[N+:13]([C:16]1[CH:23]=[CH:22][CH:21]=[CH:20][C:17]=1[CH2:18][N:9]1[C:7](=[O:8])[C:5]2=[CH:6][CH:1]=[CH:2][CH:3]=[C:4]2[C:10]1=[O:11])([O-:15])=[O:14]

참가 물질

4

반응물 2

HCID 119212-Nitrobenzyl chlorideHCID 3356745Potassium phthalimide

생성물 1

HCID 3195372-[(2-nitrophenyl)methyl]isoindole-1,3-dione

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

The mixture of 54.0 of N-potassium phthalimide, 50.0 g of o-nitrobenzyl chloride and 120 ml of dimethylformamide is refluxed for 3 hours and poured into 900 ml of ice-water while stirring. After 30 minutes, it is filtered, and the residue washed with water, to yield the N-o-nitrobenzyl-phthalimide melting at 190°-209°.

후처리

  1. temperatureis refluxed for 3 hours
  2. filtrationit is filtered
  3. washthe residue washed with water

출처 및 근거

ORD 기록
ord-eead5c0713aa4ff4979b78921b536494
출처 데이터셋
uspto-grants-1982_12
특허 번호
US04362666

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