3-(3-Amino-1H-pyrazol-1-yl)propanenitrile → HCID 54298987, 화합물
반응식
[F:1][C:2]([F:8])([F:7])[CH2:3][N:4]=[C:5]=[S:6].[NH2:9][C:10]1[CH:14]=[CH:13][N:12]([CH2:15][CH2:16][C:17]#[N:18])[N:11]=1>C(#N)C>[F:1][C:2]([F:8])([F:7])[CH2:3][NH:4][C:5](=[S:6])[NH:9][C:10]1[CH:14]=[CH:13][N:12]([CH2:15][CH2:16][C:17]#[N:18])[N:11]=1참가 물질
4
실험 절차
2,2,2-Trifluoroethylisothiocyanate (3.4 g.) was added to a solution of 3-amino-1-(2-cyanoethyl)-pyrazole (2.72 g.) in acetonitrile (10 ml.) and the solution left at room temperature for 18 hours. The mixture was evaporated to dryness and the residue recrystallised from ethanol to give 3-[3-(2,2,2-trifluoroethyl)thioureido]-1-(2-cyanoethyl)pyrazole, m.p. 164°-165°.
후처리
- customThe mixture was evaporated to dryness
- customthe residue recrystallised from ethanol
출처 및 근거
- ORD 기록
- ord-64eb143b8f6f40d9b506d8cf040ea338
- 출처 데이터셋
- uspto-grants-1982_12
- 특허 번호
- US04362728
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