Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl p-toluenesulfonate → 2-Fluoro-1-methylpyridinium p-toluenesulfonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl p-toluenesulfonate | HCID 6645 | — |
| 반응물 | 2-Fluoropyridine | HCID 9746 | — |
| 생성물 | 2-Fluoro-1-methylpyridinium p-toluenesulfonate | HCID 171631 | 95% |
반응 단계
2-fluoro-1-methylpyridinium tosylate is prepared by adding 18.6 g (0.1 mol.) of paratoluen sulphonate methyl ester to 9.7 g (0.1 mol.) of 2-fluoropyridine, heating the resultant mixture for about 20 minutes at 120° C. and cooling the heated mixture to yield 25 g of crystalline 2-fluoro-1-methylpyridinium tosylate (95%). This crystalline starting material is subsequently washed with ether and then dried.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04365067 |
| 출처 데이터셋 | uspto-grants-1982_12 |
| ORD ID | ord-073630c234b4488e8a0ae44a4bae84a0 |
| 출처 메모 | uspto-grants-1982_12 |