2-(Chloromethyl)pyridine 1-oxide → HCID 178478899, 화합물

HRID 1902863노트

반응식

HRID 1902863 반응식
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[N:9]=[C:10]1[NH:14][CH2:13][CH2:12][N:11]1[OH:15].[Cl:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N+:19]=1[O-:24].CC(C)=O.[ClH:29]>O1CCOCC1>[ClH:16].[ClH:29].[F:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[C:3]=1[N:9]=[C:10]1[NH:14][CH2:13][CH2:12][N:11]1[O:15][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N+:19]=1[O-:24]

참가 물질

5

반응물 3

HCID 2655032-(Chloromethyl)pyridine 1-oxideHCID 19044839Acetone hydrogen chlorideHCID 178526277HCID 178526277, 화합물

생성물 1

HCID 178478899HCID 178478899, 화합물

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

From 2-[(2,6-difluorophenyl)imino]-1-hydroxy-imidazolidine and 2-chloromethyl-pyridine N-oxide there is obtained, in analogy to the details in Example 1,2-([{2-[(2,6-difluorophenyl)imino]-1-imidazolidinyl}oxy]methyl)-pyridine 1-oxide dihydrochloride of melting point 188°-189° (acetone/hydrogen chloride in dioxane).

출처 및 근거

ORD 기록
ord-d75679cb844e4f339e7e79ce8ebfba31
출처 데이터셋
uspto-grants-1982_12
특허 번호
US04366160

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