Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Phenoxy-4-(4-formylpiperazino)pyrimidine → 2-Phenoxy-4-piperazinopyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Phenoxy-4-(4-formylpiperazino)pyrimidine | HCID 13869571 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-Phenoxy-4-piperazinopyrimidine | HCID 13869563 | 64% |
반응 단계
2-Phenoxy-4-(4-formylpiperazino)pyrimidine (2.6 g) in methanol (27 ml) and 2 N hydrochloric acid (6.9 ml) was left at room temperature for 24 hours and then heated on a steam bath for 30 minutes. The solvent was evaporated in vacuo and the residue re-crystallized twice from isopropanol to give 2-phenoxy-4-piperazinopyrimidine (1.5 g) characterized spectroscopically, and used directly.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04435401 |
| 출처 데이터셋 | uspto-grants-1984_03 |
| ORD ID | ord-dc8b28cf533f46818e4d50a65d641ddf |
| 출처 메모 | uspto-grants-1984_03 |