Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → N-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-2H-indazol-4-amine monohydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-Chloro-4,5-dihydroimidazole | HCID 236236 | — |
| 반응물 | 2-Chloroimidazoline sulfate | HCID 12503398 | — |
| 반응물 | 2-Methyl-2H-indazol-4-amine | HCID 15413170 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-2H-indazol-4-amine monohydrochloride | HCID 121924 | — |
반응 단계
4 g 4-amino-2-methyl-indazole is dissolved in 120 ml THF. The solution is treated with a solution of 2-chloro-imidazoline base, which is prepared from 10 g 2-chloro-imidazoline sulfate (prepared according to J. Heteroc. Chem. 11, 258) with 2 n NaOH in methylene chloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04436913 |
| 출처 데이터셋 | uspto-grants-1984_03 |
| ORD ID | ord-da576370875c43da9bcb668ba62b50f3 |
| 출처 메모 | uspto-grants-1984_03 |