Sulfuric Acid → Methyl 4-dimethylaminobenzoate

HRID 1904031

반응식

HRID 1904031 반응식
[CH3:1][N:2]([CH3:12])[C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][CH:4]=1.S(=O)(=O)(O)O.[C:18](=O)(O)[O-].[Na+]>CO>[CH3:18][O:8][C:7](=[O:9])[C:6]1[CH:10]=[CH:11][C:3]([N:2]([CH3:12])[CH3:1])=[CH:4][CH:5]=1

참가 물질

5

반응물 3

HCID 1118Sulfuric AcidHCID 120924-(Dimethylamino)benzoic acidHCID 516892Sodium Bicarbonate

생성물 1

HCID 70994Methyl 4-dimethylaminobenzoate

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

23 g of 4-dimethylaminobenzoic acid was dissolved in 200 ml of methanol to which was added 2 ml of concentrated sulfuric acid and the mixture was refluxed with heating for 2 days. After cooling, the reaction mixture was poured into an aqueous solution of sodium bicarbonate and the crystals thus deposited were collected by filtration, washed with water and dried to obtain 24 g of 4-dimethylaminobenzoic acid methyl ester having a melting point of 101° to 102° C.

후처리

  1. temperaturethe mixture was refluxed
  2. temperaturewith heating for 2 days
  3. temperatureAfter cooling
  4. filtrationthe crystals thus deposited were collected by filtration
  5. washwashed with water
  6. customdried

출처 및 근거

ORD 기록
ord-05ee31fdce14478aabec7f1a824e6376
출처 데이터셋
uspto-grants-1984_03
특허 번호
US04439519

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