Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 4-Dimethylaminomethyl-2-hydroxymethylpyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Ammonium Persulfate | HCID 62648 | — |
| 반응물 | 4-pyridinemethanamine, N,N-dimethyl- | HCID 264946 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-Dimethylaminomethyl-2-hydroxymethylpyridine | HCID 13292601 | — |
반응 단계
Ammonium persulphate (102.7 g) in water (200 ml) was added over 40 minutes to a refluxing solution of 4-dimethylaminomethylpyridine (40.86 g), methanol (450 ml), water (210 ml) and concentrated sulphuric acid (30 ml). The resulting solution was refluxed for 2 hours, water (300 ml) was added and the methanol was distilled off. The cooled solution was basified and extracted with chloroform to give 4-dimethylaminomethyl-2-hydroxymethylpyridine (19.65 g) b.p. 92°-120°/0.06 mm Hg.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04439609 |
| 출처 데이터셋 | uspto-grants-1984_03 |
| ORD ID | ord-c7eefca3e0a14bd684887e664777da8b |
| 출처 메모 | uspto-grants-1984_03 |