Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 7-chloro-1H-pyrazolo[4,3-B]pyridine-6-carboxylate → ethyl 7-n-butylamino-1H-pyrazolo [4,3-b]pyridine-6-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 7-chloro-1H-pyrazolo[4,3-B]pyridine-6-carboxylate | HCID 20038759 | — |
| 용매 | Butylamine | HCID 8007 | — |
| 생성물 | ethyl 7-n-butylamino-1H-pyrazolo [4,3-b]pyridine-6-carboxylate | HCID 20038776 | 135.3% |
반응 단계
Ethyl 7-chloro-1H-pyrazolo[4,3-b]pyridine-6-carboxylate (3.5 g, 15.5 mmol) was dissolved in n-butylamine (25 ml) and stirred at room temperature for 3 h. Excess butylamine was removed in vacuo and the residual solid was washed well with water, and recrystallised from ethyl acetate to give ethyl 7-n-butylamino-1H-pyrazolo [4,3-b]pyridine-6-carboxylate (2.75 g, 67%), m.p. 164°-170° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04837238 |
| 출처 데이터셋 | uspto-grants-1989_06 |
| ORD ID | ord-c7eda3542d964d179234801c23ff0d71 |
| 출처 메모 | uspto-grants-1989_06 |