Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methane → Dl-Phenylalanine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methane | HCID 297 | — |
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 5-(Phenylmethyl)-2,4-imidazolidinedione | HCID 73565 | — |
| 생성물 | Dl-Phenylalanine | HCID 994 | 72% |
반응 단계
95.1 g (0.5 mole) of 5-benzyl-hydantoin are heated to boiling in 350 ml of a 20% sodium hydroxide solution for 30 hours. The reaction mixture is clarified with activated charcoal and acidified with concentrated hydrochloric acid (pH 2). The precipitate (hydrantoinic acid) is filtered off and the phenyl alanine is precipitated from the filtrate as described in Example 11. Thus 59.5 g of the dry desired compound are obtained, yield 72%. Purity: 97.5% (according to HPLC).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04647694 |
| 출처 데이터셋 | uspto-grants-1987_03 |
| ORD ID | ord-6e1f3bdc80a248e58d49025324ccd378 |
| 출처 메모 | uspto-grants-1987_03 |